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Human Growth Hormone
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History of HGH

Page 7
The History of HGH
Since the FDA approval, major clinics have opened all over the US, Europe and other parts of the world. Dr. Edmund Chein, who first used his treatment on himself at age 42 and later opened a clinic, has had thousands of people pass through his clinic, including movie stars and high powered executives. Significantly, the largest group is physicians who make up 20% of his patient population. The director of Cenegenics, one of the largest anti aging clinics in the world, based out of Las Vegas, reports that 25% of their patient population is made up of doctors.

According to Chein, "there has not been one treatment failure. It's a slam dunk. This is 100% effective. I tell my patients if I can't get the blood levels of your hormones to look like that of a 20 year old, you can get all your money refunded. He also guarantees the results: a gain in bone density of 1.5 to 2.5% every six months; a loss of 10 to 12% of body fat, and a gain of 8 to 10 % in muscle mass every six months. "The changes in body fat to lean mass ratio will continue, he says, until the body composition has reverted to that of a twenty year old. And then it will stay that way."

The US Food and Drug Administration (FDA) in 2003 approved a new use for Humatrope, for the long term treatment of children with idiopathic (of unknown origin) short stature, also called non growth hormone deficient short stature. "Short stature" has been defined by the American Association of Clinical Endocrinologists and the Growth Hormone Research Society as height more than 2 standard deviations (SD) below the mean for age and sex.

This corresponds to the shortest 2.3% of children. This new indication restricts therapy to children who are even shorter, specifically more than 2.25 SD below the mean for age and sex, or the shortest 1.2% of children. For example, for 10 year old boys and girls, this would correspond to heights of less than 4' 1" inch. This would further correspond to heights of less than 5' 3" and 4' 11" in adult men and women, respectively. In clinical studies, the drug added several inches to the children's eventual height.

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