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Adult Growth Hormone Deficiency

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Diagnosis / Criteria
Adult Growth Hormone Deficiency is a condition in adults caused by the low or lack of secretion of somatotropin by the anterior pituitary gland. Somatotropin is another name for growth hormone. Hormones are chemical messages produced by special cells in glands and other organs of the body. A syndrome is a set of signs and symptoms that occur together and result from the same cause.

A single measurement of growth hormone levels is rarely useful, since growth hormone concentration is normally low most of the day and is released in pulses, not a steady secretion. Therefore, a lack of response to standard growth hormone stimulation tests is required for accurate diagnosis.

The diagnosis of Adult Growth Hormone Deficiency also requires a prior history of childhood growth hormone deficiency or a history of organic pituitary disease. After a review of all criteria, an adult endocrinologist will make the diagnosis.

Somatotropin Replacement Therapy (SRT)
The goals of treatment of Somatotropin Replacement Therapy (SRT) are to restore to as great an extent as possible, normal body function, including energy, metabolism and body composition. Somatotropin Replacement Therapy (SRT) is biosynthetic growth hormone replacement.

Source:
The Human Growth Foundation
Contributions made by:
Lorraine Sosnowski, BSN, CRNI, Ann Arbor, MI
Brian Stabler, Ph.D., UNC Chapel Hill, Chapel Hill, NC
Michael O. Thorner, M.B., D.Sc.
UVA Health Sciences Center
Charlottesville, VA.
Reviewed by the HGF Education Committee
1998
www.hgfound.org

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