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Adult Growth Hormone Deficiency

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The Pituitary Gland and the Hypothalamus
The pituitary gland, known as the "master gland," produces several hormones that control the functions of other glands. It is located in the middle of the skull below the part of the brain called the hypothalamus.

The pituitary gland secretes its hormones in response to a chemical message from the hypothalamus, the part of the brain to which it is connected.

The pituitary gland has two distinct parts: the anterior (front) lobe and the posterior (rear) lobe. The anterior lobe produces six major hormones: one for the production of breast milk, two for reproduction, one for thyroid function, one for adrenal function, and one is somatotropin, which influences growth and metabolism (chemical and physical processes to maintain life).

The hypothalamus stimulates the hormone release from the anterior pituitary; these hormones then act elsewhere in the body. When the pituitary gland is removed or destroyed, hormone secretion is lost.

When one or more hormones are lost, this is known as Hypopituitarism; when the pituitary gland is completely removed or destroyed and all hormone secretion is lost, this is referred to as Panhypopituitarism.

Source:
The Human Growth Foundation
Contributions made by:
Lorraine Sosnowski, BSN, CRNI, Ann Arbor, MI
Brian Stabler, Ph.D., UNC Chapel Hill, Chapel Hill, NC
Michael O. Thorner, M.B., D.Sc.
UVA Health Sciences Center
Charlottesville, VA.
Reviewed by the HGF Education Committee
1998
www.hgfound.org

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